The purpose of this paper is to examine the theory of risk management concerning the changes in the global paradigm of the post-COVID-19 era and to establish the measure of safety state concept. As much as the 1918 Spanish Flu or the First and Second World Wars, the ‘3.11 COVID-19 Pandemic’ is expected to transform the global society. The governance related to the role and the safety of the country is also at its turning point. While the concept of a “welfare state” was introduced in contrast to a “warfare state” after experiencing World War II, “safety state” is expected to draw attention in the post-COVID-19 era. The composition of this paper is as follows. Section 1 suggests an analysis framework that attempts to categorize the marked changes in various domains due to the spread of the infectious disease and challenges the inherited obstacles caused by the COVID19 pandemic. Section 2 considers ‘national security’ by examining political-ideological responses and paradigm shifts. It also discusses the denationalistic aspects of geoenvironmental engineering. Section 3 analyzes ‘economic security’ from the perspective of uncertainty and crisis management. Section 4 reviews ‘human security’ that includes social safety and community-related agendas. Section 5 is integrated with the science and technological issue of the Fourth Industrial Revolution, known as ‘technical security’. Lastly, Section 6 (Conclusion) theorizes the noted changes in the paradigm for each domain with the notions of security, thereby presenting the challenges in the uncertainty and outlines the global risk factors in the disaster management of the post-COVID-19 Pandemic.